Activation of AMPK/mTOR-driven autophagy and inhibition of NLRP3 inflammasome by saxagliptin ameliorate ethanol-induced gastric mucosal damage
Hany H. Arab, Ahmed M. Ashour, Amany M. Gad, Ayman M. Mahmoud, Ahmed M. Kabel
Topics & Concepts
AutophagyAMPKPI3K/AKT/mTOR pathwayInflammasomeSaxagliptinChemistryEthanolPharmacologyCell biologyCancer researchSignal transductionMedicineApoptosisBiochemistryBiologyDiabetes mellitusMetforminProtein kinase AEndocrinologyPhosphorylationReceptorSitagliptinAutophagy in Disease and TherapyAlcohol Consumption and Health EffectsInflammasome and immune disorders