Nobel Prize 2020 in Chemistry honors CRISPR: a tool for rewriting the code of life
Lukas Westermann, Björn Neubauer, Michael Köttgen
Abstract
Age-related hearing loss (ARHL) is the most prevalent sensory deficit in the elderly and constitutes the third highest risk factor for dementia. Lifetime noise exposure, genetic predispositions for degeneration, and metabolic stress are assumed to be the major causes of ARHL. Both noise-induced and hereditary progressive hearing have been linked to decreased cell surface expression and impaired conductance of the potassium ion channel K
Topics & Concepts
RewritingCRISPRCode (set theory)Programming languageChemistryComputer scienceBiochemistryGeneSet (abstract data type)CRISPR and Genetic EngineeringInnovation and Socioeconomic DevelopmentGenetics, Aging, and Longevity in Model Organisms