Tetrazine as a general phototrigger to turn on fluorophores
Axel Loredo, Juan Tang, Lushun Wang, Kuan‐Lin Wu, Zane Peng, Han Xiao
Abstract
-nitrobenzyl and nitrophenethyl groups), this study affords a new photoactivation mechanism, in which the quencher is photodecomposed to restore the fluorescence upon light irradiation. Because of the exclusive use of tetrazine as a photoquencher in the design of fluorogenic probes, we anticipate that our current study will significantly facilitate the development of novel photoactivatable fluorophores.
Topics & Concepts
TetrazineFluorophoreTurn (biochemistry)ChemistryFluorescencePhysicsBiochemistryOpticsOrganic chemistryClick Chemistry and ApplicationsPhotochromic and Fluorescence ChemistryAdvanced biosensing and bioanalysis techniques