Design of a multilayer lung chip with multigenerational alveolar ducts to investigate the inhaled particle deposition
Yan Qiu, Chao Lu, Fubing Bao, Guoqing Hu
Abstract
We present a multilayer lung chip to mimic passive breathing and highlight its potential as an innovative, cost-effective, and ethical approach to study aerosol deposition for health assessment and drug delivery in the lung.
Topics & Concepts
Particle depositionExhalationParticle (ecology)Deposition (geology)AerosolMaterials scienceLungBiomedical engineeringNanotechnologyMicrofluidicsParticle sizeChemistryChemical engineeringEngineeringMedicineAnesthesiaBiologyInternal medicinePaleontologyEcologyOrganic chemistrySedimentInhalation and Respiratory Drug DeliveryAerosol Filtration and Electrostatic PrecipitationMicrofluidic and Bio-sensing Technologies