MTMR7 suppresses the phenotypic switching of vascular smooth muscle cell and vascular intimal hyperplasia after injury via regulating p62/mTORC1-mediated glucose metabolism
Xiongshan Sun, Yao Yang, Yao Yang, Weiwei Zhao, Mingliang Wang, Yingmei Chen, Jia Wang, Dachun Yang, Yongjian Yang, Yongjian Yang
Topics & Concepts
mTORC1Intimal hyperplasiaPhenotypeVascular smooth muscleNeointimal hyperplasiaHyperplasiaMetabolismPhenotypic switchingCarbohydrate metabolismCell biologyInternal medicineBiologyEndocrinologyMedicineSmooth muscleSignal transductionBiochemistryGenePI3K/AKT/mTOR pathwayStentRestenosisAngiogenesis and VEGF in CancerMuscle Physiology and DisordersCerebrovascular and genetic disorders