Dual-mode endogenous and exogenous sensitization of tumor radiotherapy through antifouling dendrimer-entrapped gold nanoparticles
Chao Yang, Yue Gao, Yu Fan, Liu Cao, Jin Li, Yulong Ge, Wenzhi Tu, Yong Liu, Xueyan Cao, Xiangyang Shi
Abstract
The developed zwitterionic Au DENPs may be used as a promising platform for dual-mode endogenously and exogenously sensitized RT of other tumor types.
Topics & Concepts
SensitizationChemistryIn vivoGene silencingEndogenyGene knockdownCancer researchCell biologyDendrimerCancer cellRadioresistanceDownregulation and upregulationBiophysicsCancerCell cultureBiologyImmunologyBiochemistryGeneBiotechnologyGeneticsNanoplatforms for cancer theranosticsRNA Interference and Gene DeliveryCancer Research and Treatments