The Regulation of Selenoproteins in Diabetes: A New Way to Treat Diabetes
Jing Liang, Yiwen He, Chunxia Huang, Fengjie Ji, Xihong Zhou, Yulong Yin, Yulong Yin
Abstract
Selenium is an essential micronutrient required for the synthesis and function of selenoproteins, most of which are enzymes involved in maintaining oxidative balance in the body. Diabetes is a group of metabolic disorders characterized by high blood glucose levels over a prolonged period of time. There are three main types of diabetes: type 1, type 2, and gestational diabetes. This review summarizes recent advances in the field of diabetes research with an emphasis on the roles of selenoproteins on metabolic disturbance in diabetes. We also discuss the interaction between selenoproteins and glucose and lipid metabolism to provide new insights into the prevention and treatment of diabetes.