Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells
Kazuki Takeishi, Alexandra Collin de l’Hortet, Yang Wang, Kan Handa, Jorge Guzman‐Lepe, Kentaro Matsubara, Kazutoyo Morita, Sae Jang, Nils Haep, Rodrigo M. Florentino, Fangchao Yuan, Ken Fukumitsu, Kimimasa Tobita, Wendell Q. Sun, Jonathan Franks, Evan R. Delgado, Erik M. Shapiro, Nicolás A. Fraunhoffer, Andrew W. Duncan, Hiroshi Yagi, Tomoji Mashimo, Ira J. Fox, Alejandro Soto–Gutiérrez
Abstract
) rats.
Topics & Concepts
Induced pluripotent stem cellDecellularizationTransplantationStem cellCell biologyBiologyHuman liverParenchymaChimera (genetics)PathologyCancer researchEmbryonic stem cellIn vitroMedicineInternal medicineBiochemistryExtracellular matrixGeneTissue Engineering and Regenerative MedicineLiver physiology and pathologyPluripotent Stem Cells Research