Chinese medicine Tongxinluo capsule protects against blood-brain barrier disruption after ischemic stroke by inhibiting the low-density lipoprotein receptor-related protein 1 pathway in mice
Liping Chang, Li Hu, Cong Wei, Hui Zhang, Shen Liu
Topics & Concepts
OccludinBlood–brain barrierDownregulation and upregulationTight junctionStroke (engine)MedicinePharmacologyBrain ischemiaIschemiaReceptorLDL receptorInternal medicineChemistryLipoproteinCell biologyBiologyCentral nervous systemCholesterolBiochemistryGeneEngineeringMechanical engineeringBarrier Structure and Function StudiesLipid metabolism and disordersNeurological Disease Mechanisms and Treatments