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BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells

Hyungseok Seo, Edahí González‐Avalos, Wade Zhang, Payal Ramchandani, Chao Yang, Chan‐Wang Jerry Lio, Anjana Rao, Patrick G. Hogan

2021Nature Immunology350 citationsDOIOpen Access PDF

Topics & Concepts

IRF4Cancer researchImmunologyBiologyGeneGeneticsTranscription factorCAR-T cell therapy researchImmune Cell Function and InteractionT-cell and B-cell Immunology
BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells | Litcius