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Patient derived ex vivo tissue slice cultures demonstrate a profound DNA double-strand break repair defect in HPV-positive oropharyngeal head and neck cancer

Henrike Zech, Joanna Berger, Wael Mansour, Lena Nordquist, Clara Marie von Bargen, Lara Bußmann, Agnes Oetting, Sabrina Christiansen, Nikolaus Möckelmann, Arne Böttcher, Chia‐Jung Busch, Cordula Petersen, Christian Betz, Kai Rothkamm, Malte Kriegs, Sabrina Köcher, Thorsten Rieckmann

2022Radiotherapy and Oncology18 citationsDOI

Topics & Concepts

Ex vivoRadiosensitivityIn vivoPathologyHead and neck squamous-cell carcinomaHead and neck cancerImmunofluorescenceBiologyCell cultureCellRadiation therapyCancer researchMedicineAntibodyInternal medicineImmunologyGeneticsBiotechnologyHead and Neck Cancer StudiesEsophageal Cancer Research and TreatmentDNA Repair Mechanisms
Patient derived ex vivo tissue slice cultures demonstrate a profound DNA double-strand break repair defect in HPV-positive oropharyngeal head and neck cancer | Litcius