Multiparametric MRI and <sup>18</sup>F-PSMA-1007 PET/CT for the Detection of Clinically Significant Prostate Cancer
Bastiaan M. Privé, Bas Israël, Marcel J. R. Janssen, Marloes M. G. van der Leest, Maarten de Rooij, Jolique A. van Ipenburg, Marianne A. Jonker, Steffie M. B. Peters, Michel de Groot, Patrik Zámecnik, Alexander Hoepping, Joyce G. R. Bomers, Martin Gotthardt, J.P. Michiel Sedelaar, Jelle O. Barentsz, Inge M. van Oort, James Nagarajah
Abstract
Fluorine 18 prostate-specific membrane antigen 1007 PET/CT showed good sensitivity and moderate specificity for the detection of clinically significant prostate cancer, effectively ruling this out in 93% of participants with Prostate Imaging Reporting and Data System category 3 lesions.
Topics & Concepts
MedicineProstate cancerCancer detectionNuclear medicineProstateCancerRadiologyMagnetic resonance imagingInternal medicineProstate Cancer Diagnosis and TreatmentProstate Cancer Treatment and ResearchRadiomics and Machine Learning in Medical Imaging