Development of Au@NiO decorated polypyrrole composite for non-Enzymatic electrochemical sensing of cholesterol
A. Nagarajan, V. Sethuraman, T.M. Sridhar, R. Sasikumar
Abstract
In this study, glassy carbon electrode modified by Au@NiO decorated polypyrrole nanocomposite (Au@NiO/PPy-GCE) was fabricated for sensing of cholesterol by non-enzymatic electrochemical method . The composite was characterized by XRD , XPS and morphological studies were examined using FE-SEM and TEM. The redox properties of cholesterol were investigated by cyclic voltammetry . When differential pulse voltammetry was employed to sense cholesterol, it exhibited a linear range from 1.0 × 10 -5 to 1.0 × 10 -4 M, with the sensitivity 7.6 µA µM −1 cm −2 and detection limit 5.8 x10 -7 M. Hence, this composite has excellent practical applications towards the fabrication of commercial sensors.
Topics & Concepts
Differential pulse voltammetryPolypyrroleCyclic voltammetryElectrochemistryMaterials scienceNanocompositeComposite numberX-ray photoelectron spectroscopyDetection limitNon-blocking I/ORedoxGlassy carbonChemical engineeringNuclear chemistryElectrodeNanotechnologyChemistryComposite materialOrganic chemistryChromatographyMetallurgyPhysical chemistryCatalysisEngineeringElectrochemical sensors and biosensorsConducting polymers and applicationsElectrochemical Analysis and Applications