Immunological mechanisms of fecal microbiota transplantation in recurrent <i>Clostridioides difficile</i> infection
Lucas F Soveral, Gabriela G Korczaguin, P Schmidt, Isabel S Nunes, Camilo Fernandes, Carlos R. Zárate-Bladés
Abstract
after FMT seems to rely on a pivotal role of regulatory T cells, which would be responsible for the reduction of several cells and soluble inflammatory mediators, ensuing normalization of the intestinal mucosal immune system. In this minireview, we analyze recent advances in these immunological aspects associated with the efficacy of FMT.
Topics & Concepts
ClostridioidesFecal bacteriotherapyImmune systemImmunologyGut floraClostridium difficileMicrobiomeTransplantationBiologyMedicineMicrobiologyBioinformaticsInternal medicineAntibioticsClostridium difficile and Clostridium perfringens researchMicroscopic ColitisGastrointestinal motility and disorders