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Guillain Barre Syndrome associated with COVID-19 Infection: A Case Report

Sujan Shrestha, Niranjan KC, Niroj Hirachan

2021Journal of Nepal Medical Association29 citationsDOIOpen Access PDF

Abstract

Coronavirus Disease has become a global pandemic after its emergence at the end of 2019 as a cluster of pneumonia. Apart from respiratory symptoms, neurologic complications are also common, mostly in hospitalized patients. More than 80 percent of patients have neurological symptoms during their disease course of which most common is encephalopathy. However, data on neurological complications like Guillain-Barré syndrome associated with coronavirus-2019 are scarce. Here, we report a case of a 64-years-old female patient with typical clinical and electrophysiological manifestations of Acute motor axonal neuropathy variant, who was reported positive with polymerase chain reaction for severe acute respiratory syndrome coronavirus-2, 13 days before the onset of acute bilateral weakness of extremities, areflexia, and normal sensory examination. Cerebrospinal fluid and electrophysiological examination were also suggestive. The neurological symptoms improved during treatment with immunoglobulins. Quick recognition of symptoms and diagnosis is important in the management of Guillain-Barré syndrome associated with coronavirus-2019.

Topics & Concepts

MedicineGuillain-Barre syndromePneumoniaCoronavirusEncephalopathyDiseasePediatricsWeaknessNeurological examinationCerebrospinal fluidCoronavirus disease 2019 (COVID-19)Internal medicineSurgeryInfectious disease (medical specialty)Peripheral Neuropathies and DisordersLong-Term Effects of COVID-19Nerve injury and regeneration
Guillain Barre Syndrome associated with COVID-19 Infection: A Case Report | Litcius