The impact of medication-related osteonecrosis of the jaws on the quality of life in cancer patients
Raquel D’Aquino Garcia Caminha, Patrícia Pereira Tavares de Alcântara, Caroline Gomes Carvalho, Verônica Caroline Brito Reia, Ana Lúcia Álvares Capelozza, PS. Santos
Abstract
BACKGROUND: To evaluate the impact of oral health on the quality of life (QOL) of individuals undergoing cancer treatment at the time of diagnosis of medication-related osteonecrosis of the jaw (MRONJ). MATERIAL AND METHODS: The present cross-sectional study analyzed patients with MRONJ from 2013 to 2019. The collected data included demographic data, base disease, medications associated with MRONJ, route of administration and time of use, signs, symptoms, and tomographic features of acute MRONJ, staging according to American Association of Oral and maxillofacial Surgeons position paper 2014 (AAOMS), type of dental treatment performed, outcome, and the responses to the Oral Health Impact Profile questionnaire (OHIP-14). Statistical analysis was performed using the Tukey test to study the association between oral condition and the QOL. A p-value of less than 0.05 was considered statistically significant. RESULTS: = 0.747). The other dimensions did not show statistically significant results. CONCLUSIONS: Medication-related osteonecrosis of the jaw, quality of life, oral health, OHIP-14.