Impact of genotype-predicted CYP2D6 metabolism on clinical effects and tolerability of metoprolol in patients after myocardial infarction – a prospective observational study
Anne Kristine Anstensrud, Espen Molden, H Haug, Rehman Qazi, Hysen Muriq, Linn E. Fosshaug, Olav Spigset, Erik Øie
Topics & Concepts
MetoprololCYP2D6MedicineTolerabilityInternal medicinePharmacologyDebrisoquineMyocardial infarctionPharmacogeneticsAdverse effectCardiologyGenotypeBiologyMetabolismCytochrome P450GeneBiochemistryPharmacogenetics and Drug MetabolismEicosanoids and Hypertension PharmacologyAntiplatelet Therapy and Cardiovascular Diseases