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A Well‐Coupled Supramolecular System Accelerates Photophosphorylation

Zibo Li, Fanchen Yu, Shuhao Wang, Yuyang Cai, Yang Xu, Yue Li, Jinbo Fei, Junbai Li

2024Angewandte Chemie International Edition7 citationsDOIOpen Access PDF

Abstract

Abstract Supramolecular assembly allows multiple chemical/bio‐components integrated as one system for cascade biochemical reactions. Herein the graphitic carbon nitrides (g‐C 3 N 4 ) as photocatalyst trapped in a dipeptide hydrogel covering adenosine triphosphate (ATP) synthase accelerates the photophosphorylation through ATP synthesis. Self‐assembled N ‐fluorenylmethoxycarbonyl diphenylalanine (Fmoc‐FF) as nanofibrils to allow g‐C 3 N 4 nanosheets are embedded as a complex Fmoc‐FF/g‐C 3 N 4 hydrogel. Fmoc‐FF gel exhibits good electronic coupling with g‐C 3 N 4 , which enables a photo‐induced proton generation. The transmembrane proton gradient can be established by ATP synthase‐lipid reconstituted on the surface of the Fmoc‐FF/g‐C 3 N 4 hydrogel to enhance the ATP synthesis. It indicates that the Fmoc‐FF/g‐C 3 N 4 /ATP synthase‐lipid film can possess a longer‐term ATP production capability and allow repeated immersion for sustained ATP production. Such a hydrogel‐supported ATP synthesis platform is achieved by a procedure at a larger scale.

Topics & Concepts

PhotophosphorylationATP synthaseSupramolecular chemistryChemiosmosisChemistryAdenosine triphosphateGraphitic carbon nitrideElectrochemical gradientV-ATPaseTransmembrane proteinBiophysicsATPaseCatalysisBiochemistryPhotocatalysisEnzymeMoleculeMembraneOrganic chemistryBiologyChloroplastGeneReceptorBoron Compounds in ChemistryNanoplatforms for cancer theranosticsNeonatal Health and Biochemistry