Quercetin ameliorates neuroinflammatory and neurodegenerative biomarkers in the brain and improves neurobehavioral parameters in a repeated intranasal amyloid-beta exposed model of Alzheimer's disease
Vaibhav Lasure, Avtar Singh Gautam, Rakesh Kumar Singh
Abstract
: Quercetin was found to be a potent antioxidant, anti-inflammatory compound with protection against neurodegenerative damage and improved learning and cognitive memory in a repeated Aβ-exposure model of AD.
Topics & Concepts
NeuroinflammationAmyloid betaNasal administrationMedicineDiseaseAlzheimer's diseasePharmacologyNeuroscienceQuercetinAmyloid (mycology)HyperphosphorylationAntioxidantPsychologyChemistryInternal medicinePathologyBiochemistryKinaseAlzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsBiochemical effects in animals