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S3I-201, a selective stat3 inhibitor, ameliorates clinical symptoms in a mouse model of experimental autoimmune encephalomyelitis through the regulation of multiple intracellular signalling in Th1, Th17, and treg cells

Sheikh F. Ahmad, Mushtaq Ahmad Ansari, Ahmed Nadeem, Saleh A. Bakheet, Haneen A. Al‐Mazroua, Hatun A. Alomar, Mohammed A. Al‐Hamamah, Sabry M. Attia

2023Multiple Sclerosis and Related Disorders15 citationsDOI

Topics & Concepts

Experimental autoimmune encephalomyelitisFOXP3RAR-related orphan receptor gammaMedicineSTAT3ImmunologyImmune systemMultiple sclerosisPharmacologyBiologySignal transductionCell biologyCytokine Signaling Pathways and InteractionsImmune Cell Function and InteractionMast cells and histamine
S3I-201, a selective stat3 inhibitor, ameliorates clinical symptoms in a mouse model of experimental autoimmune encephalomyelitis through the regulation of multiple intracellular signalling in Th1, Th17, and treg cells | Litcius