A modified Fangji Huangqi decoction ameliorates pulmonary artery hypertension via phosphatidylinositide 3-kinases/protein kinase B-mediated regulation of proliferation and apoptosis of smooth muscle cells in vitro and in vivo
Zhifeng Xue, Mengen Zhou, Yiman Liu, Honglin Qin, Yixuan Li, Yan Zhu, Jian Yang
Topics & Concepts
Pulmonary arteryPharmacologyPulmonary hypertensionApoptosisProtein kinase BMedicinePI3K/AKT/mTOR pathwayKinaseRight ventricular hypertrophyLungIn vivoLY294002Cancer researchInternal medicineBiologyCell biologyBiochemistryBiotechnologyPulmonary Hypertension Research and TreatmentsInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisChronic Obstructive Pulmonary Disease (COPD) Research