Pd-Catalyzed Photochemical Alkylative Functionalization of C═C and C═N Bonds
Ganesh Chandra Upreti, Tavinder Singh, Kirti Khanna, Anand Singh
Abstract
The development of excited-state palladium-catalyzed alkylative cyclization of acrylamides and the alkylation of quinoxalinones is described. The application of a variety of primary, secondary, and tertiary unactivated alkyl halides as alkyl radical precursors and the use of a simple catalyst system are the highlights of this reactivity manifold. The reactions exhibit wide scope, occur under mild conditions, and furnish the products in excellent yields.
Topics & Concepts
CatalysisChemistryAlkylationHalideAlkylReactivity (psychology)PalladiumPrimary (astronomy)Photoredox catalysisSurface modificationHalogenationOrganic chemistryCombinatorial chemistryPhotochemistryPhotocatalysisPhysical chemistryMedicineAstronomyPhysicsAlternative medicinePathologyCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsOxidative Organic Chemistry Reactions