Cryptogenic organising pneumonia: current understanding of an enigmatic lung disease
Ganesh Raghu, Keith C. Meyer
Abstract
Organising pneumonia (OP) is currently recognised as a nonspecific lung injury response that is associated with a variety of imaging patterns obtained with high-resolution computed tomography (HRCT) of the chest and is characterised histopathologically by the presence of inflammatory cells and a connective tissue matrix within distal airspaces of the lungs. OP is associated with many conditions that include connective tissue disorders, various infections, drug reactions, hypersensitivity pneumonitis and aspiration. When OP cannot be linked to an associated condition and appears to be idiopathic, it is termed cryptogenic organising pneumonia.
Topics & Concepts
MedicineHypersensitivity pneumonitisPneumoniaConnective tissueLungCryptogenic Organizing PneumoniaPathologyMixed connective tissue diseaseAspiration pneumoniaHigh-resolution computed tomographyDiseaseInternal medicineInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisMedical Imaging and Pathology StudiesSarcoidosis and Beryllium Toxicity Research