Exploring the mechanism of Levistolide A in the treatment of lung cancer cells based on network analysis, molecular docking and experimental validation
Lei Zhao, Jingyu Wang, Yue Han, Qingkun Wang, Wenqing Yang, Yu Zhang, Zhenhua Lin, Lianhua Zhu, Junjie Piao
Topics & Concepts
ApoptosisLung cancerChemistryFlow cytometryIntracellularCancer researchBlotCancer cellA549 cellCell growthMechanism (biology)CancerCell cultureMechanism of actionDocking (animal)KEGGCytotoxicityTreatment of lung cancerCellGrowth inhibitionCell biologyComputational biologyMTT assayPharmacologySignal transductionIntrinsic apoptosisSynthesis and biological activityGenomics, phytochemicals, and oxidative stressCancer Mechanisms and Therapy