Application of organometallic catalysts for the synthesis of <i>o</i>-tolyl benzonitrile, a key starting material for sartans
Anupam Jana, V. Ravichandiran, Sharada Prasanna Swain
Abstract
This review describes methods for the synthesis of o -tolyl benzonitrile, such as Pd-, Ni-catalyzed Suzuki, Negishi and Kumada couplings reactions.
Topics & Concepts
BenzonitrileChemistryNegishi couplingCatalysisOrganic chemistryOrganometallic chemistryKey (lock)EcologyBiologyCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsSynthetic Organic Chemistry Methods