Amentoflavone inhibits tumor necrosis factor-α-induced migration and invasion through AKT/mTOR/S6k1/hedgehog signaling in human breast cancer
Shuai Qiu, Yimeng Zhou, Jin Tae Kim, Cheng Bao, Hong Jin Lee, Jing Chen
Abstract
mediating AKT/mTOR/S6K1 signaling. Amentoflavone should be considered as a potent food ingredient for the retardation of mammary tumorigenesis.
Topics & Concepts
P70-S6 Kinase 1AmentoflavoneCancer researchPI3K/AKT/mTOR pathwayHuman breastHedgehog signaling pathwayProtein kinase BBreast cancerHedgehogMedicineSignal transductionBiologyCancerInternal medicineCell biologyPharmacologyHedgehog Signaling Pathway StudiesCancer-related Molecular PathwaysNonmelanoma Skin Cancer Studies