Highly diastereoselective annulation of 2-substituted 3-nitro-2<i>H</i>-chromenes with hemicurcuminoids and curcuminoids <i>via</i> a double and triple Michael reaction cascade
Nikolay S. Zimnitskiy, Alexey Yu. Barkov, Иван А. Кочнев, Igor B. Kutyashev, Vladislav Yu. Korotaev, Vyacheslav Ya. Sosnovskikh
Abstract
One-pot stereoselective methods for the synthesis of hexahydro-9 H -benzo[ c ]chromen-9-ones and hexahydro-1 H ,6 H -chromeno[6,5- c ]chromen-1-ones have been developed.
Topics & Concepts
ChemistryAnnulationNitroCascadeMichael reactionTriple bondStereochemistryMedicinal chemistryOrganic chemistryDouble bondCatalysisAlkylChromatographySynthesis of Organic CompoundsMulticomponent Synthesis of HeterocyclesCarbohydrate Chemistry and Synthesis