Localized gastric distension disrupts slow-wave entrainment leading to temporary ectopic propagation: a high-resolution electrical mapping study
Chih-Hsiang Alexander Chan, Zahra Aghababaie, Niranchan Paskaranandavadivel, Recep Avci, Leo K. Cheng, Timothy R. Angeli
2021American Journal of Physiology-Gastrointestinal and Liver Physiology20 citationsDOIOpen Access PDF
Abstract
This study presents the discovery of temporary dysrhythmic ectopic pacemakers in the distal stomach caused by localized gastric distension. Distension-induced dysrhythmias are an interesting physiological phenomenon that can inform the design of new interventional and electrophysiological protocols for both research and the clinic. The observation of distension-induced dysrhythmias also contributes to our understanding of stretch-sensitivity in the gut and may play an important role in normal and abnormal postprandial physiology.
Topics & Concepts
DistensionGastric distensionMedicineBalloonStomachEntrainment (biomusicology)ElectrophysiologyPostprandialAnesthesiaSurgeryInternal medicineRhythmInsulinGastrointestinal motility and disordersPhonocardiography and Auscultation TechniquesGastroesophageal reflux and treatments