Non-viral delivery of the CRISPR/Cas system: DNA<i>versus</i>RNA<i>versus</i>RNP
Yi Lin, Ernst Wagner, Ulrich Lächelt
Abstract
genome editing in patients has not been reached so far. The article summarises the characteristics and differences of each format, provides an overview of the published delivery strategies and highlights recent examples of delivery systems including the status of clinical applications.
Topics & Concepts
CRISPRRNADNAVirologyChemistryDelivery systemMolecular biologyComputational biologyBiologyGeneBiochemistryPharmacologyCRISPR and Genetic EngineeringViral Infections and Immunology ResearchRNA Interference and Gene Delivery