Simultaneous cognate epitope recognition by bovine CD4 and CD8 T cells is essential for primary expansion of antigen-specific cytotoxic T-cells following ex vivo stimulation with a candidate Mycobacterium avium subsp. paratuberculosis peptide vaccine
Gaber S. Abdellrazeq, Lindsay M. Fry, Mahmoud M. Elnaggar, John P. Bannantine, David A. Schneider, William Chamberlin, Asmaa H. Mahmoud, Kun Taek Park, Victoria Hulubei, William C. Davis
Topics & Concepts
Cytotoxic T cellBiologyEpitopeCTL*AntigenMHC class IIMHC class IAntigen-presenting cellCD8Antigen presentationT cellMajor histocompatibility complexMonoclonal antibodyMolecular biologyImmunologyImmune systemAntibodyIn vitroBiochemistryMycobacterium research and diagnosisImmune Cell Function and InteractionImmunotherapy and Immune Responses