Inhibition of JAK1/STAT3 pathway by 2-methoxyestradiol ameliorates psoriatic features in vitro and in an imiquimod-induced psoriasis-like mouse model
Jiaxuan Tang, Chaofan Liu, Shiying Liu, Xing Zhou, Jinghao Lu, Ming Li, Lubing Zhu
Topics & Concepts
HaCaTPsoriasisSTAT3Psoriasis Area and Severity IndexAngiogenesisCancer researchMedicineApoptosisSTAT proteinVascular endothelial growth factorImmunologyEndocrinologyPharmacologyInternal medicineChemistryIn vitroBiochemistryVEGF receptorsPsoriasis: Treatment and PathogenesisDermatology and Skin DiseasesCytokine Signaling Pathways and Interactions