Direct Hydrodecarboxylation of Aliphatic Carboxylic Acids: Metal- and Light-Free
Euan B. McLean, David T. Mooney, David Burns, Ai‐Lan Lee
Abstract
A mild and inexpensive method for direct hydrodecarboxylation of aliphatic carboxylic acids has been developed. The reaction does not require metals, light, or catalysts, rendering the protocol operationally simple, easy to scale, and more sustainable. Crucially, no additional H atom source is required in most cases, while a broad substrate scope and functional group tolerance are observed.
Topics & Concepts
ChemistryCatalysisFunctional groupSubstrate (aquarium)Rendering (computer graphics)MetalCombinatorial chemistryScope (computer science)Organic chemistryEcologyComputer scienceComputer graphics (images)BiologyPolymerProgramming languageCatalytic C–H Functionalization MethodsCarbon dioxide utilization in catalysisAsymmetric Hydrogenation and Catalysis