Novel 4-(piperazin-1-yl)quinolin-2(1H)-one bearing thiazoles with antiproliferative activity through VEGFR-2-TK inhibition
Abdelfattah Hassan, Mohamed Badr, Heba A. Hassan, Dalia Abdelhamid, Gamal El‐Din A. Abuo‐Rahma
Topics & Concepts
ChemistryAcetamideStereochemistryIC50SorafenibApoptosisCytotoxic T cellCytotoxicityCell cyclePharmacologyDocking (animal)In vitroBiochemistryCancer researchHepatocellular carcinomaMedicineBiologyOrganic chemistryNursingSynthesis and biological activityQuinazolinone synthesis and applicationsSynthesis and Characterization of Heterocyclic Compounds