Increased S1P induces S1PR2 internalization to blunt the sensitivity of colorectal cancer to 5-fluorouracil via promoting intracellular uracil generation
Yuhang Zhang, Shu‐Xiang Cui, Shengbiao Wan, Shuhua Wu, Xian‐Jun Qu
Topics & Concepts
InternalizationCancer researchUnfolded protein responseCell biologyChemistryBiologyEndoplasmic reticulumCellBiochemistrySphingolipid Metabolism and SignalingLipid Membrane Structure and BehaviorEndoplasmic Reticulum Stress and Disease