Determinants of Impaired Peak Oxygen Uptake in Breast Cancer Survivors: JACC: CardioOncology Primer
Stephen Foulkes, Mark J. Haykowsky, Todd Li, Jing Wang, Megan Kennedy, Amy A. Kirkham, Richard B. Thompson, D. Ian Paterson, André La Gerche, Edith Pituskin
Abstract
•Exercise intolerance is common among breast cancer survivors.•Exercise intolerance in breast cancer survivors is related to cardiac, vascular, and skeletal muscle impairments.•Holistic rehabilitation or pharmacological therapies are needed to address these impairments.
Topics & Concepts
Breast cancerMedicineExercise intoleranceRehabilitationInternal medicineCancerPhysical therapySkeletal muscleOncologyPhysical medicine and rehabilitationHeart failureChemotherapy-induced cardiotoxicity and mitigationCancer survivorship and careChildhood Cancer Survivors' Quality of Life