Intense interval exercise induces lactate accumulation and a greater suppression of acylated ghrelin compared with submaximal exercise in middle-aged adults
Seth F. McCarthy, Derek P.D. Bornath, Claudia Jarosz, Jessica A. L. Tucker, Philip J. Medeiros, Kenji A. Kenno, Tom J. Hazell
Abstract
We explored the effects of submaximal, near maximal, and supramaximal intensity exercise on appetite regulation in middle-aged adults. Our data support the intensity-dependent effect of exercise on acylated ghrelin suppression that is closely related to lactate accumulation, though there appears to be little effect on anorexigenic hormones [active peptide tyrosine tyrosine (PYY), active glucagon-like peptide-1 (GLP-1)], overall appetite, or free-living energy intake. These data support previous results in younger adults where lactate was implicated in the exercise-induced suppression of acylated ghrelin.
Topics & Concepts
GhrelinInternal medicineAppetiteEndocrinologyPhysical exerciseMedicineHormonePeptide YYInterval trainingExercise intensityPeptide hormoneNeuropeptideReceptorHeart rateNeuropeptide Y receptorBlood pressureRegulation of Appetite and ObesityBiochemical Analysis and Sensing TechniquesEating Disorders and Behaviors