Novel long-acting brimonidine tartrate loaded-PCL/PVP nanofibers for versatile biomedical applications: fabrication, characterization and antimicrobial evaluation
Samar A. Salim, Noha M. Badawi, Shahira H. EL‐Moslamy, Elbadawy A. Kamoun, Baher A. Daihom
Abstract
antimicrobial assessments revealed good activities for all scaffolds against most of the investigated human pathogens, particularly the one prepared with 9% BT which showed superiority in the antimicrobial effect over other scaffolds. To conclude, our findings proved the capability of nanofibers in loading BT and improving its repurposed antimicrobial efficacy. Therefore, it could be a promising carrier for BT to be used in combating numerous human pathogens.
Topics & Concepts
BrimonidineAntimicrobialFabricationNanotechnologyNanofiberCharacterization (materials science)Materials scienceChemistryCombinatorial chemistryOrganic chemistryMedicineOphthalmologyIntraocular pressureAlternative medicinePathologyElectrospun Nanofibers in Biomedical ApplicationsConducting polymers and applicationsElectrochemical sensors and biosensors