Increased Neuronal Nitric Oxide Synthase in Alzheimer's Disease Mediates Spontaneous Calcium Signaling and Divergent Glutamatergic Calcium Responses
Rachelle Balez, Claire H. Stevens, Kerstin Lenk, Simon Maksour, Kuldip Sidhu, Greg T. Sutherland, Lezanne Ooi
Abstract
Nitrosative stress is a feature of Alzheimer's disease (AD).
Topics & Concepts
GlutamatergicCalciumNitric oxide synthaseCalcium signalingNitric oxideNeuroscienceDiseaseNeuronal Nitric Oxide SynthaseChemistryBiologyMedicineInternal medicineBiochemistryEndocrinologyGlutamate receptorReceptorMitochondrial Function and PathologyNeuroscience and Neuropharmacology ResearchNitric Oxide and Endothelin Effects