<i>Gastrodia elata</i> polysaccharide alleviates Parkinson's disease <i>via</i> inhibiting apoptotic and inflammatory signaling pathways and modulating the gut microbiota
Qingxia Gan, Maoyao Peng, Haobo Wei, Linlin Chen, Xiao-yan Chen, Zi-han Li, Guangqin An, Yuntong Ma
Abstract
, increased the content of microbial metabolites SCFAs in the colon and increased the level of occludin that repairs the intestinal barrier of PD mice. In conclusion, this study is expected to provide a theoretical basis for the development and application of functional products with GEP from the perspective of neuroprotective effects.
Topics & Concepts
Gastrodia elataPolysaccharideApoptosisSignal transductionGut floraChemistryBiologyPharmacologyBiochemistryMedicineTraditional Chinese medicinePathologyAlternative medicineBiological and pharmacological studies of plantsGinger and Zingiberaceae researchGinseng Biological Effects and Applications