Design, synthesis, molecular docking and antiproliferative activity of some novel benzothiazole derivatives targeting EGFR/HER2 and TS
Khaled R.A. Abdellatif, Amany Belal, Mohammed T. El‐Saadi, Noha H. Amin, Eman G. Said, Loah R. Hemeda
Topics & Concepts
BenzothiazoleChemistryDocking (animal)PyrimidineLapatinibMoietyMTT assayCombinatorial chemistryEGFR inhibitorsIn vitroEnzymeStereochemistryEpidermal growth factor receptorBiochemistryCancerReceptorInternal medicineNursingBreast cancerTrastuzumabMedicineSynthesis and biological activityComputational Drug Discovery MethodsQuinazolinone synthesis and applications