Exploring the bioactive landscape: peptides and non-peptides from the human microbiota
Abdul Bari Shah, Hyeonjae Cho, Sang Hee Shim
Abstract
The human microbiota, consisting of trillions of bacteria from six main phyla, produces peptide and non-peptide secondary metabolites which have antibacterial properties vital to medicine and biotechnology. These metabolites influence biological processes linked to diseases, yet much remains unknown. This review explores their structures and functions, aiming to spur novel metabolite discovery and advance drug development.
Topics & Concepts
Computational biologyAntimicrobial peptidesPeptideChemistryBiologyBiochemistryProbiotics and Fermented FoodsGut microbiota and healthProtein Hydrolysis and Bioactive Peptides