Determination and Simulation of Menadiol Diacetate Solubility in 14 Solvents at Temperatures from 283.15 to 323.15 K
Xinyi Lü, Xiaotong Yang, Xiaoli Wu, Jidong Wang, Zhong Zhao
Abstract
In this paper, the solubility of menadiol diacetate in nine alcohols (methanol, ethanol, n -propanol, i -propanol, n -butanol, i -butanol, n -amyl alcohol, i -amyl alcohol, and cyclohexanol) and five n -alkyl acetates (methyl acetate, ethyl acetate, n -propyl acetate, n -butyl acetate, and amyl acetate) was experimentally measured with the aid of a laser dynamic device at temperatures from 283.15 to 323.15 K. The solubility of menadiol diacetate as a function of temperature was regressed in terms of three semiempirical solubility models (Apelblat, van’t Hoff, and λ h ), two activity coefficient solubility models (Wilson and NRTL), and the Jouyban model. The thermodynamic mixing properties (mixing Gibbs energy, entropy, and enthalpy) of the solutions were estimated in terms of the measured solubility data and the regressed parameters of the Wilson model.