Zinc–Brønsted acid mediated practical hydrotrifluoromethylation of alkenes with CF<sub>3</sub>Br
Deqian Peng, Fan Wu, Xueqi Zhao, Wei Chen, Yuan Wen, Li Zhang, Suhua Li
Abstract
Hydrotrifluoromethylation of alkenes was developed through a novel generation of CF 3 ˙ via the combination of Zn and PhCO 2 H with CF 3 Br.
Topics & Concepts
ChemistryBrønsted–Lowry acid–base theoryZincMedicinal chemistryOrganic chemistryCatalysisFluorine in Organic ChemistryInorganic Fluorides and Related Compounds