Lapachol in the Design of a New Ruthenium(II)-Diphosphine Complex as a Promising Anticancer Metallodrug
Katia M. Oliveira, João Honorato, Felipe C. Demidoff, Mário Sérgio Schultz, Chaquip D. Netto, Márcia R. Cominetti, Rodrigo S. Corrêa, Alzir A. Batista
Topics & Concepts
ChemistryCisplatinCytotoxicityRutheniumStereochemistryReactive oxygen speciesLawsoneMolar conductivityCancer cellApoptosisIn vitroBiochemistryCancerOrganic chemistrySurgeryInternal medicineMetalMedicineCatalysisChemotherapyBioactive Compounds and Antitumor AgentsMetal complexes synthesis and propertiesSynthesis and Biological Evaluation