Investigating the Chemolithoautotrophic and Formate Metabolism of Nitrospira moscoviensis by Constraint-Based Metabolic Modeling and <sup>13</sup> C-Tracer Analysis
Christopher E. Lawson, Aniela B. Mundinger, Hanna Koch, Tyler B. Jacobson, Coty A. Weathersby, Mike S. M. Jetten, Martin Pabst, Daniel Amador‐Noguez, Daniel R. Noguera, Katherine D. McMahon, Sebastian Lücker
Abstract
Nitrospira spp. are globally abundant nitrifying bacteria in soil and aquatic ecosystems and in wastewater treatment plants, where they control the oxidation of nitrite to nitrate. Despite their critical contribution to nitrogen cycling across diverse environments, detailed understanding of their metabolic network and prediction of their function under different environmental conditions remains a major challenge.
Topics & Concepts
NitrospiraEnvironmental chemistryNitriteNitrateNitrogen cycleWastewaterSewage treatmentNitrificationAquatic ecosystemChemistryEnvironmental scienceEcologyBiologyEnvironmental engineeringNitrogenOrganic chemistryMicrobial Metabolic Engineering and BioproductionWastewater Treatment and Nitrogen RemovalBiofuel production and bioconversion