<i>In Silico</i> Genotyping of Escherichia coli Isolates for Extraintestinal Virulence Genes by Use of Whole-Genome Sequencing Data
Anna Maria Malberg Tetzschner, James R. Johnson, Brian Johnston, Ole Lund, Flemming Scheutz
Abstract
Extraintestinal pathogenic Escherichia coli (ExPEC) is the leading cause in humans of urinary tract infection and bacteremia. The previously published web tool VirulenceFinder ( http://cge.cbs.dtu.dk/services/VirulenceFinder/ ) uses whole-genome sequencing (WGS) data for in silico characterization of E. coli isolates and enables researchers and clinical health personnel to quickly extract and interpret virulence-relevant information from WGS data.
Topics & Concepts
GenotypingIn silicoBiologyVirulenceEscherichia coliWhole genome sequencingGenomeMicrobiologyGeneticsGeneDNA sequencingGenotypeEscherichia coli research studiesProbiotics and Fermented FoodsBacteriophages and microbial interactions