Litcius/Paper detail

Design and synthesis of the novel, selective WZ4002 analogue as EGFR-L858R/T790M tyrosine kinase inhibitors for targeted drug therapy in non-small-cell lung cancer (NSCLC)

Rahul Pawara, Iqrar Ahmad, Deepika Nayak, Sateesh Belamkar, Sanjay J. Surana, Chanakya Nath Kundu, Chandragauda Patil, Harun Patel

2021Journal of Molecular Structure29 citationsDOI

Topics & Concepts

T790MGefitinibChemistryEpidermal growth factor receptorEGFR inhibitorsIC50MutantTyrosine kinaseCancer researchCell cultureLung cancerCell growthPharmacologyBiochemistryReceptorIn vitroOncologyMedicineBiologyGeneticsGeneLung Cancer Treatments and MutationsCancer therapeutics and mechanismsHER2/EGFR in Cancer Research