Modeling the Magnetic-Hyperthermia Response of Linear Chains of Nanoparticles with Low Anisotropy: A Key to Improving Specific Power Absorption
Daniela P. Valdés, Enio Lima, Roberto D. Zysler, E. De Biasi
Abstract
Magnetic fluid hyperthermia is an emerging cancer therapy for the selective destruction of tumors via localized heating. Here magnetic interactions among nanoparticles can drastically modify the specific power absorption, but the effects of interactions in chainlike arrangements are not well understood. This theoretical study employs a probabilistic model that goes beyond linear-response theory, accounting for the effects of temperature, frequency, and corrections to the local field on each nanoparticle. The analysis addresses different chain configurations and experimental conditions, which is crucial to understanding situations where agglomeration is almost inevitable.
Topics & Concepts
Absorption (acoustics)Materials sciencePower (physics)NanoparticleAnisotropyMagnetic fieldMagnetic nanoparticlesKey (lock)Condensed matter physicsNanotechnologyComputer sciencePhysicsThermodynamicsQuantum mechanicsComposite materialComputer securityNanoparticle-Based Drug DeliveryCharacterization and Applications of Magnetic NanoparticlesIron oxide chemistry and applications