Litcius/Paper detail

Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF)

Xinyu Wu, Mingchen Wang, Yu Cao, Ying Xu, Ziqun Yang, Yiluan Ding, Jing Lu, Jie Zheng, Cheng Luo, Kehao Zhao, Shijie Chen

2023Bioorganic Chemistry10 citationsDOI

Topics & Concepts

ChemistryEnzymeDocking (animal)BiochemistryHomogeneousHigh-throughput screeningBinding siteFluorescenceTransferaseComputational biologyPhysicsBiologyMedicineQuantum mechanicsNursingThermodynamicsGlycosylation and Glycoproteins ResearchCarbohydrate Chemistry and SynthesisGalectins and Cancer Biology