Alcohol consumption and epigenetic age acceleration in young adults
Drew R. Nannini, Brian Joyce, Yinan Zheng, Tao Gao, Jun Wang, Lei Liu, David R. Jacobs, Pamela J. Schreiner, Chunyu Liu, Qi Dai, Steve Horvath, Ake T. Lu, Kristine Yaffe, Philip Greenland, Donald M. Lloyd‐Jones, Lifang Hou
Abstract
= 0.004) consumption with chronological age, with younger participants exhibiting a higher average in GAA compared to older participants. No associations were observed with the other measures of epigenetic aging. These results suggest cumulative liquor and total alcohol consumption and recent binge drinking may alter age-related epigenetic changes as captured by GAA. With the increasing aging population and widespread consumption of alcohol, these findings may have potential implications for lifestyle modification to promote healthy aging.